The Deignan-class Destroyer was designed in 1920 initially as an improvement to the Clemson class in regards to range, speed and firepower. There were only six ships built, using the cancelled Clemson-Class DD Designations, and the rest of the planned DDs cancelled after the stock market crash of '29. All 6 ended up in the Asiatic Fleet, based out of Cavite Naval Base, Philippines, and were summarily lost in various actions at the beginning of the war.
The Muscatatuck-class Cutter was designed in 1921 as a solution to resolve the issues of speed and firepower lacking in Cutters at the time. With the development of the 5"/25 as a large caliber AAA gun in the USN, trials were tested to see how effective it was against surface targets by an enterprising young Coast Guard Lieutenant. Needless to say, the Coast Guard adapted it for its Muscatatuck-class Interdiction Cutters. 10 of these cutters were constructed, 4 of them in PNW at PSNS and Seattle-Tacoma Shipyards.